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March Tourney Betting Lines and Odds That Are Interesting

Betting lines, spreads, totals and more betting odds for every game of the 2025 men’s NCAA tournament.

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Men’s March Madness 2025: Betting Odds, Lines, Totals, and BPI

As the 2025 men’s NCAA tournament kicks off, 68 teams are ready to battle it out for glory, and the Auburn Tigers are strutting in as the No. 1 overall seed. After a disappointing SEC tournament, they’re on a mission to prove they’re the best in the land.

The SEC made a bold statement by sending 14 teams to the Big Dance, but they’ll face stiff competition from a formidable Houston squad and the return of a healthy Cooper Flagg with the Duke Blue Devils.

Here’s a rundown of the betting lines, spreads, and totals for Friday’s first-round matchups and Saturday’s second-round games. Remember, odds are accurate as of publication time. For the latest odds, check out ESPN BET.

Friday – Round 1

(9) Baylor Bears vs. (8) Mississippi State Bulldogs -1.5

East Region, 12:15 p.m. Lenovo Center, Raleigh, NC

  • Baylor: 19-14, 10-10 in Big 12 play
  • Mississippi State: 21-12, 8-10 in SEC play
  • Moneyline: Mississippi State (-125), Baylor (+105)
  • Total: 145.5
  • BPI Projection: Baylor by 3, straight up: 61.6%

(15) Robert Morris Colonials vs. (2) Alabama Crimson Tide -22.5

East Region, 12:40 p.m. Rocket Arena, Cleveland, OH

  • Robert Morris: 26-8, 15-5 in Horizon play
  • Alabama: 25-8, 13-5 in SEC play
  • Moneyline: Alabama (-7500), Robert Morris (+2000)
  • Total: 166.5
  • BPI Projection: Alabama by 21, straight up: 96.7%

(14) Lipscomb Bisons vs. (3) Iowa State Cyclones -14.5

South Region, 1:30 p.m. Fiserv Forum, Milwaukee, WI

  • Lipscomb: 25-9, 14-4 in ASUN play
  • Iowa State: 24-9, 13-7 in Big 12 play
  • Moneyline: Iowa State (-1600), Lipscomb (+800)
  • Total: 142.5
  • BPI Projection: Iowa State by 15.6, straight up: 92.4%

(12) Colorado State Rams vs. (5) Memphis Tigers -1.5

West Region, 2 p.m. Climate Pledge Arena, Seattle, WA

  • Colorado State: 25-9, 16-4 in MW play
  • Memphis: 28-5, 16-2 in American play
  • Moneyline: Colorado State (-120), Memphis (+EVEN)
  • Total: 146.5
  • BPI Projection: Memphis by 0.8, straight up: 53.3%

(16) Mount St. Mary’s Mountaineers vs. (1) Duke Blue Devils -32.5

East Region, 2:50 p.m. Lenovo Center, Raleigh, NC

  • Mount St. Mary’s: 22-12, 12-8 in MAAC play
  • Duke: 31-3, 19-1 in ACC play
  • Moneyline: Duke (-50000), Mount St. Mary’s (+3000)
  • Total: 140.5
  • BPI Projection: Duke by 30.6, straight up: 99.3%

(10) Vanderbilt Commodores vs. (7) Saint Mary’s Gaels -4.5

East Region, 3:15 p.m. Rocket Arena, Cleveland, OH

  • Vanderbilt: 20-12, 8-10 in SEC play
  • Saint Mary’s: 28-5, 17-1 in WCC play
  • Moneyline: Saint Mary’s (-190), Vanderbilt (+160)
  • Total: 135.5
  • BPI Projection: Saint Mary’s by 4.2, straight up: 66.2%

(11) North Carolina Tar Heels vs. (6) Ole Miss Rebels -1.5

South Region, 4:05 p.m. Fiserv Forum, Milwaukee, WI

  • North Carolina: 22-13, 13-7 in ACC play
  • Ole Miss: 22-11, 10-8 in SEC play
  • Moneyline: North Carolina (-130), Ole Miss (+110)
  • Total: 155.5
  • BPI Projection: North Carolina by 1.6, straight up: 56.3%

(13) Grand Canyon Lopes vs. (4) Maryland Terrapins -10.5

West Region, 4:35 p.m. Climate Pledge Arena, Seattle, WA

  • Grand Canyon: 26-7, 13-3 in WAC play
  • Maryland: 25-8, 14-6 in Big Ten play
  • Moneyline: Maryland (-650), Grand Canyon (+425)
  • Total: 149.5
  • BPI Projection: Maryland by 11.4, straight up: 86.2%

(16) Norfolk State Spartans vs. (1) Florida Gators -28.5

West Region, 6:50 p.m. Lenovo Center, Raleigh, NC

  • Norfolk State: 24-10, 11-3 in MEAC play
  • Florida: 29-4, 14-4 in SEC play
  • Moneyline: Florida (-15000), Norfolk State (+3000)
  • Total: 153.5
  • BPI Projection: Florida by 22.3, straight up: 97.2%

(14) Troy Trojans vs. (3) Kentucky Wildcats -11.5

Midwest Region, 7:10 p.m. Fiserv Forum, Milwaukee, WI

  • Troy: 23-10, 13-5 in Sun Belt play
  • Kentucky: 22-11, 10-8 in SEC play
  • Moneyline: Kentucky (-750), Troy (+475)
  • Total: 151.5
  • BPI Projection: Kentucky by 12.9, straight up: 88.8%

(10) New Mexico Lobos vs. (7) Marquette Golden Eagles -3.5

South Region, 7:25 p.m. Rocket Arena, Cleveland, OH

  • New Mexico: 26-7, 17-3 in MW play
  • Marquette: 23-10, 13-7 in Big East play
  • Moneyline: Marquette (-175), New Mexico (+150)
  • Total: 152.5
  • BPI Projection: Marquette by 5.6, straight up: 70.9%

(13) Akron Zips vs. (4) Arizona Wildcats -14.5

East Region, 7:35 p.m. Climate Pledge Arena, Seattle, WA

  • Akron: 28-6, 17-1 in MAC play
  • Arizona: 22-12, 14-6 in Big 12 play
  • Moneyline: Arizona (-1200), Akron (+700)
  • Total: 167.5
  • BPI Projection: Arizona by 15.8, straight up: 92.7%

(9) Oklahoma Sooners vs. (8) UConn Huskies -5.5

West Region, 9:25 p.m. Lenovo Center, Raleigh, NC

  • Oklahoma: 20-13, 6-12 in SEC play
  • UConn: 23-10, 14-6 in Big East play
  • Moneyline: UConn (-215), Oklahoma (+180)
  • Total: 148.5
  • BPI Projection: UConn by 5.4, straight up: 70.5%

(11) Xavier Musketeers vs. (6) Illinois Fighting Illini -3.5

Midwest Region, 9:45 p.m. Fiserv Forum, Milwaukee, WI

  • Xavier: 21-11, 13-7 in Big East play
  • Illinois: 21-12, 12-8 in Big Ten play
  • Moneyline: Illinois (-155), Xavier (+135)
  • Total: 160.5
  • BPI Projection: Illinois by 2.6, straight up: 60.1%

(15) Bryant Bulldogs vs. (2) Michigan State Spartans -18.5

South Region, 10 p.m. Rocket Arena, Cleveland, OH

  • Bryant: 23-11, 14-2 in Am. East play
  • Michigan State: 27-6, 17-3 in Big Ten play
  • Moneyline: Michigan State (-2500), Bryant (+1200)
  • Total: 152.5
  • BPI Projection: Michigan State by 17.1, straight up: 93.9%

(12) Liberty Flames vs. (5) Oregon Ducks -6.5

East Region, 10:10 p.m. Climate Pledge Arena, Seattle, WA

  • Liberty: 28-6, 13-5 in C-USA play
  • Oregon: 24-9, 12-8 in Big Ten play
  • Moneyline: Oregon (-290), Liberty (+240)
  • Total: 139.5
  • BPI Projection: Oregon by 7.1, straight up: 75.6%

Saturday – Round 2

(12) McNeese Cowboys vs. (4) Purdue Boilermakers -5.5

Midwest Region, 12:10 p.m. Amica Mutual Pavilion, Providence, RI

  • McNeese: 27-6, 19-1 in Southland play
  • Purdue: 22-11, 13-7 in Big Ten play
  • Moneyline: Purdue (-240), McNeese (+200)
  • Total: 143.5
  • BPI Projection: Purdue by 7.5, straight up: 76.8%

(10) Arkansas Razorbacks vs. (2) St. John’s Red Storm -7.5

West Region, 2:40 p.m. Amica Mutual Pavilion, Providence, RI

  • Arkansas: 20-13, 8-10 in SEC play
  • St. John’s: 30-4, 18-2 in Big East play
  • Moneyline: St. John’s (-300), Arkansas (+250)
  • Total: 144.5
  • BPI Projection: St. John’s by 5.7, straight up: 71.3%

(5) Michigan Wolverines vs. (4) Texas A&M Aggies -2.5

South Region, 5:15 p.m. Ball Arena, Denver, CO

  • Michigan: 24-9, 14-6 in Big Ten play
  • Texas A&M: 22-10, 11-7 in SEC play
  • Moneyline: Texas A&M (-140), Michigan (+120)
  • Total: 140.5
  • BPI Projection: Texas A&M by 2.1, straight up: 58.1%

(11) Drake Bulldogs vs. (3) Texas Tech Red Raiders -7.5

West Region, 6:10 p.m. INTRUST Bank Arena, Wichita, KS

  • Drake: 30-3, 17-3 in MVC play
  • Texas Tech: 25-8, 15-5 in Big 12 play
  • Moneyline: Texas Tech (-380), Drake (+290)
  • Total: 127.5
  • BPI Projection: Texas Tech by 10.4, straight up: 84.1%

(9) Creighton Bluejays vs. (1) Auburn Tigers -8.5

South Region, 7:10 p.m. Rupp Arena, Lexington, KY

  • Creighton: 24-10, 15-5 in Big East play
  • Auburn: 28-5, 15-3 in SEC play
  • Moneyline: Auburn (-450), Creighton (+340)
  • Total: 150.5
  • BPI Projection: Auburn by 7.4, straight up: 76.5%

(6) BYU Cougars vs. (3) Wisconsin Badgers -1.5

East Region, 7:45 p.m. Ball Arena, Denver, CO

  • BYU: 24-9, 14-6 in Big 12 play
  • Wisconsin: 26-8, 13-7 in Big Ten play
  • Moneyline: BYU (-115), Wisconsin (-115)
  • Total: 154.5
  • BPI Projection: Wisconsin by 0.8, straight up: 53.2%

(8) Gonzaga Bulldogs vs. (1) Houston Cougars -4.5

Midwest Region, 8:40 p.m. INTRUST Bank Arena, Wichita, KS

  • Gonzaga: 25-8, 14-4 in WCC play
  • Houston: 30-4, 19-1 in Big 12 play
  • Moneyline: Houston (-225), Gonzaga (+190)
  • Total: 139.5
  • BPI Projection: Houston by 6.2, straight up: 72.8%

(7) UCLA Bruins vs. (2) Tennessee Volunteers -4.5

Midwest Region, 9:40 p.m. Rupp Arena, Lexington, KY

  • UCLA: 22-10, 13-7 in Big Ten play
  • Tennessee: 27-6, 12-6 in SEC play
  • Moneyline: Tennessee (-195), UCLA (+165)
  • Total: 132.5
  • BPI Projection: Tennessee by 4.6, straight up: 67.6%
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Penn State vs. Northwestern hype video

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Penn State enters Evanston at 3-1, but the Lions aren’t exactly riding into battle untouched. After opening the season with three straight wins-including a 55-13 win over Buffalo-their first Big Ten test ended in a 24-20 loss to Wisconsin. The defense is still creating havoc, with eight takeaways through four games, but now the Lions leave Happy Valley needing to prove that one defeat didn’t crack the armor.

Waiting on the shores of Lake Michigan is a Northwestern team that has been a lot more dangerous than anyone should assume. The Wildcats opened 2-0, crushed Colorado 41-7, then went into the home of No. 5 Indiana and nearly pulled off the upset before falling 29-23. Now they return home for the first game ever at the new Ryan Field-and they already beat Penn State 22-21 last season. The Wildcats have their castle. The Lions are at the gates.

Friday night, the battle begins.

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Steelers somehow lose to a Deshaun Watson-led Browns team

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The Browns did the football equivalent of showing up to the AFC North potluck, eating the best dish, and then acting surprised when they’re suddenly in charge of the whole table. Cleveland’s 27-24 win over Pittsburgh on Thursday night pushed the Browns to 3-1, put them alone in first place in the division, and extended Deshaun Watson’s latest hobby: marching the offense downfield like a man who has somewhere much better to be after midnight.

This was Watson’s third straight game-winning drive, which is the sort of stat that starts turning a team’s identity from “interesting early-season story” into “oh no, these guys might actually be real.” The Browns have spent enough years living in the land of should-have-won-and-didn’t that a divisional win like this feels especially loud. Beating the Steelers at home in prime time is never just one victory; it’s a little declaration that the old AFC North script might need a rewrite. Cleveland has momentum, confidence, and first place — three things that are usually hard to find in one Browns-shaped package. The takeaway is simple: if this is the version of Cleveland that shows up in October, the rest of the division is going to need a bigger excuse than “it was on Thursday night.”

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5 Times Athletes Shoved Their Hometown Team in a Locker

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Last night, we witnessed Massachusetts natives Cam Schlittler and Ben Rice absolutely spank their hometown team. The Sox’s asses were so red from the beating that they’re most likely going to drop tonight’s game and the Wild Card Series as well. For anyone who missed the beating, pull up a chair.

According to the NBC/AP game report, the Yankees opened the Wild Card Series by beating Boston 9–0, and two kids raised among Red Sox fans in Massachusetts administered most of the ass-kicking. Schlittler allowed just two hits and one walk while striking out 10 over 6⅓ shutout innings, while Rice went 4-for-5 with two home runs, a double and six RBIs, including an eighth-inning grand slam that turned an already bad night in Boston into something requiring a safe word. Schlittler also threw 117 pitches—the most by a Yankees postseason starter since CC Sabathia in 2012—and lowered his career ERA against Boston to an absurd 0.47. (ABC News)

But Schlittler and Rice aren’t the first athletes to grow up loving the hometown team, leave home and eventually come back wearing enemy colors. Sports history is littered with guys who returned home, looked at the team they once cheered for and essentially said, Thanks for the childhood memories. Now get in the locker.

1. Paul Pierce Beats the Lakers for the Damn Championship

Paul Pierce grew up in Southern California as a Lakers fan. Then basketball decided to play one of its better practical jokes: Pierce became the face of the Boston Celtics, spent years wearing the uniform Lakers fans despise most and eventually met Los Angeles in the 2008 NBA Finals. (NBA)

And Pierce didn’t just beat his childhood team—he took their lunch money on basketball’s biggest stage. He averaged 21.8 points, 6.3 assists and 4.5 rebounds in the six-game series, dropped 28 in Game 2 and 38 in Game 5, then walked away as Finals MVP after Boston won the championship. Imagine growing up cheering for the Lakers and eventually being personally responsible for another Celtics championship banner hanging in Boston. That’s not turning on your childhood team; that’s joining its blood enemy and burning down the family business. (Basketball Reference)

2. Will Anderson Jr. Leaves Georgia, Then Helps Alabama Punch the Bulldogs in the Mouth

Will Anderson Jr. grew up in Georgia and has talked about being a Bulldogs fan as a kid. Instead, he left home for Alabama—which is already a little like growing up in Pittsburgh and announcing you’re moving to Baltimore because you really admire the Ravens’ organizational culture.

Then came the 2021 SEC Championship Game. No. 1 Georgia arrived undefeated; Anderson and Alabama sent them home with a 41–24 ass-kicking. Anderson finished with six tackles, two tackles for loss, a sack and a quarterback pressure, helping Alabama hand Georgia its first loss of the season and claim the SEC championship. Georgia eventually got revenge in the national title game, but for one Saturday in Atlanta, the Georgia kid helped Alabama kick down the front door of his home state and take the conference trophy. (Alabama Athletics)

3. Patrick Kane Makes Buffalo Regret Letting the Local Kid Leave Town

Patrick Kane grew up in Buffalo, and playing the Sabres meant playing against the team tied to his childhood. Apparently nostalgia lasted until the puck dropped.

In January 2017, Buffalo was 56 seconds away from finally beating Chicago when the Blackhawks tied the game. Then Kane personally ended the evening 56 seconds into overtime, scoring the game-winner for a 4–3 Chicago victory after already recording two assists. At that point Kane had 13 points in 12 career games against Buffalo, and Chicago had beaten the Sabres 10 straight times. There’s returning home, and then there’s repeatedly showing up at your parents’ house, drinking their beer and beating their favorite hockey team. (NHL)

4. Auston Matthews Comes Home to Arizona and Scores Against the Team That Made Him Love Hockey

Auston Matthews’ story is particularly cruel because the Arizona Coyotes actually helped create the monster that eventually came back to beat them. Matthews grew up in Scottsdale, went to Coyotes games as a kid and rooted for the franchise before becoming the No. 1 overall pick of the Toronto Maple Leafs. (NHL)

Then in December 2017, Matthews came home for Christmas, rented a suite for family and friends and scored his first NHL goal in Arizona against—you guessed it—the Coyotes. His first-period goal put Toronto ahead 2–0 on the way to a 7–4 Maple Leafs win. Nothing says happy holidays quite like flying home, inviting 30 friends and relatives to the arena and publicly kicking the shit out of the franchise that helped inspire your career. (NHL)

5. Jonathan Quick Comes Home and Basically Ends the Rangers’ Stanley Cup Dreams

Jonathan Quick grew up in Connecticut with a connection to the Rangers and even skated at Madison Square Garden as a 12-year-old during the intermission of a Rangers game. Years later, he returned to that same building under slightly less adorable circumstances: as the goalie standing between New York and the Stanley Cup.

In Game 3 of the 2014 Stanley Cup Final, Quick stopped all 32 Rangers shots in a 3–0 Kings victory at Madison Square Garden. The shutout gave Los Angeles a suffocating 3–0 series lead, and the Kings finished the job in five games to win the Cup. Quick essentially returned to the building where he’d once been a wide-eyed kid, slammed the door on 32 shots and told an entire city, Yeah, this place is even cooler when everybody hates you. (NHL

Sometimes you leave home to chase your dreams.

Sometimes you come back and beat the shit out of them.

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